anti- CYP7B1 antibody

Our Anti-CYP7B1 Antibody, available in a 100µg size, is a vital tool for researchers studying the cytochrome P450 enzyme CYP7B1, known for its role in bile acid synthesis and steroid hormone metabolism.

CYP7B1 is involved in the conversion of cholesterol into bile acids and plays a crucial role in lipid metabolism and steroid hormone biosynthesis. Understanding the functions and regulation of CYP7B1 is essential for unraveling its contributions to cholesterol homeostasis and hormone-related disorders.

Our antibody has undergone rigorous validation for specificity and sensitivity, ensuring reliable results in your experiments. Its compact size allows for versatility in applications, whether you're conducting enzyme assays, investigating cholesterol metabolism, or exploring steroid hormone pathways. Trust in the quality of our Anti-CYP7B1 Antibody to accelerate your scientific investigations and contribute to advancements in lipid biology and endocrinology research.

Product Name

CYP7B1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Oxysterol 7alpha-hydroxylase that mediates formation of 7-alpha,25-dihydroxycholesterol(7-alpha,25-OHC) from 25-hydroxycholesterol(PubMed:10588945). Plays a key role in cell positioning and movement in lymphoid tissues: 7-alpha,25-dihydroxycholesterol(7-alpha,25-OHC) acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells(By similarity).

IMMUNOGEN INFORMATION

Immunogen

cytochrome P450, family 7, subfamily B, polypeptide 1

Synonyms

CBAS3, CP7B, CYP7B1, Cytochrome P450 7B1, Oxysterol 7 alpha hydroxylase, SPG5A

Observed MW

50-55 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

O75881

IMAGES