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SKU:FNab02183

anti- Cysteine dioxygenase type 1 antibody

anti- Cysteine dioxygenase type 1 antibody

Regular price $310.00 USD
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Our Anti-Cysteine Dioxygenase Type 1 Antibody, available in a 100µg size, is a valuable tool for researchers studying the enzyme cysteine dioxygenase type 1 (CDO1), which plays a central role in the metabolism of the amino acid cysteine.

Accurate detection and quantification of CDO1 are crucial for understanding its functions in regulating cysteine levels and its potential implications in processes such as glutathione synthesis and redox homeostasis. This antibody has been rigorously validated for specificity and sensitivity, ensuring reliable results in applications such as immunohistochemistry, immunofluorescence, and Western blotting.

With its compact size, this antibody offers versatility in experimental approaches, allowing you to explore CDO1 expression and localization in different tissues and cell types. Trust in the quality of our Anti-Cysteine Dioxygenase Type 1 Antibody to advance your research and deepen your understanding of CDO1's role in amino acid metabolism and cellular physiology.

Product Name

Cysteine dioxygenase type 1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

CDO1(cysteine dioxygenase type 1) is also named as CDO and belongs to the cysteine dioxygenase family. It is an enzyme that adds molecular oxygen to the sulfur of cysteine, converting the thiol to a sulfinic acid known as cysteinesulfinic acid(3-sulfinoalanine) and CDO1 is one of the most highly regulated metabolic enzymes responding to diet(PMID:19011731). The expression of CDO can significantly decrease the level of intracellular cysteine and this reduction is also associated with a decrease in total glutathione levels(PMID:17327371). Cysteine dioxygenase(CDO) plays a critical role in the regulation of cellular cysteine concentration andmultiple forms of CDO(23 kDa, 25 kDa, and 68 kDa) have been claimed based upon separation and detection using S

IMMUNOGEN INFORMATION

Immunogen

cysteine dioxygenase, type I

Synonyms

CDO, CDO I, CDO1, Cysteine dioxygenase type 1, cysteine dioxygenase, type I

Observed MW

23 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IP

Recommended Dilution

WB: 1:200-1:2000; IP: 1:200-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q16878

IMAGES

 

Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab02183(CDO1 antibody) at dilution of 1:100
IP Result of anti-CDO1 (IP:FNab02183, 3ug; Detection:FNab02183 1:600) with mouse liver tissue lysate 4000ug.
mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab02183(CDO1 antibody) at dilution of 1:600
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