anti- Cytochrome c antibody

Our Anti-Cytochrome c Antibody, available in a 100µg size, is a versatile polyclonal antibody designed to meet the needs of researchers investigating the pivotal role of cytochrome c in mitochondrial function and apoptosis.

Cytochrome c is a critical component of the mitochondrial electron transport chain, playing a central role in oxidative phosphorylation and ATP synthesis. Additionally, it is a key player in apoptosis, where its release from the mitochondria triggers programmed cell death. Accurate detection and quantification of cytochrome c are crucial for understanding its contributions to cellular bioenergetics and apoptosis pathways.

This polyclonal antibody has undergone rigorous validation for specificity and sensitivity, ensuring robust and reproducible results in various applications, such as immunohistochemistry, immunofluorescence, and Western blotting. Its polyclonal nature enhances the probability of recognizing different epitopes on the target protein, increasing the reliability of your experiments.

Trust in the quality of our Anti-Cytochrome c Polyclonal Antibody to advance your research and deepen your understanding of cytochrome c's multifaceted role in mitochondrial function and cellular signaling, with potential implications in cell biology and disease mechanisms.

Product Name

Cytochrome c antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Cytochrome c is a 12-15 kDa electron transporting protein located in the inner mitochondrial membrane. As a part of respiratory chain, cytochrome c plays a critical role in the process of oxidative phosphorylation and ATP producing. Besides, cytochrome c also gets implicated in apoptosis process. Upon apoptotic stimulation, cytochrome c can be released from mitochondria into cytoplasm, which is required for caspase-3 activation and the occurrence of apoptosis.

IMMUNOGEN INFORMATION

Immunogen

cytochrome c, somatic

Synonyms

CYC, CYCS, Cytochrome c, cytochrome c, somatic, HCS, THC4

Observed MW

12-15 kDa

APPLICATION

Tested Application

ELISA, IHC, WB

Recommended Dilution

WB: 1:200-1:2000；IHC: 1:20-1:400

UNIPROT INFORMATION

UniProt ID

P99999

IMAGES