anti- Cytokeratin 1-specific antibody

Our Anti-Cytokeratin 1-Specific Antibody, available in a 100µg size, is a highly specific tool for researchers investigating the role of cytokeratin 1 in various cellular processes. Cytokeratins are key structural proteins in epithelial cells and are often used as markers for epithelial differentiation and as indicators of cell health.

This antibody is designed to specifically target cytokeratin 1, ensuring accurate and reliable results in your experiments. Its compact size is ideal for a range of applications, from immunohistochemistry to Western blotting, allowing you to explore cytokeratin 1 expression in diverse tissue and cell types.

Understanding the functions and regulation of cytokeratin 1 is crucial for studies in cell biology, tissue development, and cancer research. With our Anti-Cytokeratin 1-Specific Antibody, you can delve deeper into the intricate world of cytokeratins and their significance in various biological processes.

Product Name

Cytokeratin 1-specific antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. Keratin-1 is type II keratin. It is a specific marker for terminal differentiation in mammalian epidermis. It is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. This antibody is specifically against ketatin I.

IMMUNOGEN INFORMATION

Immunogen

keratin 1

Synonyms

67 kDa cytokeratin, CK 1, CK1, Cytokeratin 1, keratin 1, KRT1

Observed MW

67 kDa

APPLICATION

Tested Application

ELISA, IP, IF, WB, IHC

Recommended Dilution

WB: 1:500-1:5000; IP: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P04264

IMAGES