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Immunohistochemistry of paraffin-embedded human colon tissue slide using FNab02221( KRT8 Antibody) at dilution of 1:200 -
Immunofluorescent analysis of HepG2 cells using FNab02221 ( KRT8 Antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) -
MCF7 cells were subjected to SDS PAGE followed by western blot with FNab02221(KRT8 antibody) at dilution of 1:1500
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SKU:FNab02221
anti- Cytokeratin 8 antibody
anti- Cytokeratin 8 antibody
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$290.00 USD
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$290.00 USD
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Our Anti-Cytokeratin 8 Antibody, available as a set of two 100µg vials, is a versatile and cost-effective solution for researchers investigating Cytokeratin 8 in various research applications. Cytokeratin 8 is a key intermediate filament protein expressed in epithelial tissues, and its accurate detection is crucial for understanding cellular structure and disease mechanisms.
These antibodies have undergone rigorous validation for specificity and sensitivity, ensuring reliable results in applications such as immunohistochemistry and Western blotting. With two separate vials, you have the flexibility to perform multiple experiments or assays while maintaining consistent and reliable results.
Cytokeratin 8 is known to be involved in maintaining the structural integrity of epithelial cells and has implications in cancer and other diseases. These antibodies provide ample material for exploration of Cytokeratin 8 expression and function in different tissues, cell types, and experimental conditions. Trust in the quality of our Anti-Cytokeratin 8 Antibody set to advance your research efficiently and comprehensively.
Product Name
Cytokeratin 8 antibody
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
BACKGROUND
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.
IMMUNOGEN INFORMATION
Immunogen
keratin 8
Synonyms
CARD2, CK 8, CK8, CYK8, Cytokeratin 8, K2C8, K8, keratin 8, KO, KRT8, Type II keratin Kb8
Observed MW
53 kDa
APPLICATION
Tested Application
ELISA, WB, IF, IHC
Recommended Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
UNIPROT INFORMATION
UniProt ID
IMAGES
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