anti- Cytokeratin 8 antibody

Our Anti-Cytokeratin 8 Antibody, available in a 100µg size, is a valuable tool for researchers studying the role of Cytokeratin 8 in the cytoskeleton and its implications in cellular structure and disease states. Cytokeratin 8 is a member of the intermediate filament family and is expressed in epithelial tissues.

Accurate detection of Cytokeratin 8 is essential for understanding its functions, including its role in maintaining the structural integrity of epithelial cells and its potential involvement in diseases such as cancer. This antibody has undergone rigorous validation for specificity and sensitivity, ensuring reliable results in applications such as immunohistochemistry and Western blotting.

With its 100µg size, this antibody provides ample material for multiple experiments, allowing you to explore Cytokeratin 8 expression and function in various epithelial tissues and pathological conditions. Trust in the quality of our Anti-Cytokeratin 8 Antibody to advance your research and deepen your understanding of the intricate roles played by Cytokeratin 8 in cellular biology.

Product Name

Cytokeratin 8 antibody

Size

100µg

Form

liquid

Purification

Protein A+G purification

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG2a

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. KRT8 is often paired with keratin 18 in vivo.

IMMUNOGEN INFORMATION

Immunogen

keratin 8

Synonyms

CARD2, CK 8, CK8, CYK8, Cytokeratin 8, K2C8, K8, keratin 8, KO, KRT8, Type II keratin Kb8

Observed MW

54 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:5000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P05787

IMAGES