anti- DAO antibody

Our Anti-DAO (D-Amino Acid Oxidase) Antibody, available in a 100µg size, is an essential tool for researchers investigating the role of DAO in the metabolism of D-amino acids and its implications in neurotransmission and neurobiology. DAO is responsible for the degradation of D-serine, an important regulator of NMDA receptor activity.

Accurate detection of DAO is crucial for understanding its functions and its involvement in conditions such as schizophrenia and neurological disorders. This antibody has undergone rigorous validation for specificity and sensitivity, ensuring reliable results in applications such as immunohistochemistry and Western blotting.

With its 100µg size, this antibody provides ample material for multiple experiments, allowing you to explore DAO expression and function in different brain regions, cell types, and disease models. Trust in the quality of our Anti-DAO Antibody to advance your research and deepen your insights into the complex roles played by DAO in neurotransmission and neurobiological processes.

Product Name

DAO antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known; it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia.

IMMUNOGEN INFORMATION

Immunogen

D-amino-acid oxidase

Synonyms

DAMOX

Observed MW

39 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P14920