anti- DARS2 antibody

Our Anti-DARS2 (Aspartyl-tRNA Synthetase 2) Antibody, available in a 100µg size, is an essential tool for researchers investigating the role of DARS2 in protein synthesis and its implications in mitochondrial biology. DARS2 is a mitochondrial enzyme critical for aminoacylation of tRNAs.

Accurate detection of DARS2 is crucial for understanding its functions and its involvement in mitochondrial diseases. This antibody has undergone rigorous validation for specificity and sensitivity, ensuring reliable results in applications such as immunofluorescence and Western blotting.

With its 100µg size, this antibody provides ample material for multiple experiments, allowing you to explore DARS2 expression and function in different cell types and mitochondrial disorders. Trust in the quality of our Anti-DARS2 Antibody to advance your research and deepen your understanding of the pivotal role played by DARS2 in mitochondrial function and disease pathogenesis.

Product Name

DARS2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. It is a mitochondrial enzyme that specifically aminoacylates aspartyl-tRNA. Mutations in this gene are associated with leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL).

IMMUNOGEN INFORMATION

Immunogen

aspartyl-tRNA synthetase 2, mitochondrial

Observed MW

74 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

Q6PI48

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