anti- DBF4 antibody

Our Anti-DBF4 (DDB1 and CUL4 Associated Factor 4) Antibody, available in a 100µg size, is a valuable tool for researchers investigating the role of DBF4 in DNA replication and cell cycle control. DBF4 is a crucial component of the Dbf4-dependent kinase complex, which regulates DNA replication initiation.

Accurate detection of DBF4 is essential for understanding its functions and its implications in genome stability and cancer. This antibody has undergone rigorous validation for specificity and sensitivity, ensuring reliable results in applications such as immunoprecipitation and immunofluorescence.

With its 100µg size, this antibody provides ample material for multiple experiments, allowing you to explore DBF4 expression and function in different cell types and cell cycle phases. Trust in the quality of our Anti-DBF4 Antibody to advance your research and deepen your insights into the intricate mechanisms governing DNA replication and cell proliferation.

Product Name

DBF4 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle.

IMMUNOGEN INFORMATION

Immunogen

DBF4 homolog

Synonyms

ASK, DBF4A, ZDBF1

Observed MW

70-80kd

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

Q9UBU7

IMAGES