anti- DBNL antibody

Our Anti-DBNL (Drebrin-like Protein) Antibody, available in a 100µg size, is a valuable tool for researchers exploring the role of DBNL in actin cytoskeleton dynamics and neuronal development. DBNL is a protein that regulates actin filament assembly and plays a pivotal role in neuronal morphogenesis.

Accurate detection of DBNL is essential for understanding its functions and its potential implications in neurodevelopmental disorders and synaptic plasticity. This antibody has undergone rigorous validation for specificity and sensitivity, ensuring reliable results in applications such as immunofluorescence and co-immunoprecipitation.

With its 100µg size, this antibody provides ample material for multiple experiments, enabling you to delve deeper into DBNL's expression and function in different neuronal populations and during various stages of development. Trust in the quality of our Anti-DBNL Antibody to advance your research and gain insights into the complex biology of neuronal morphology and plasticity.

Product Name

DBNL antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Adapter protein that binds F-actin and DNM1, and thereby plays a role in receptor-mediated endocytosis. Plays a role in the reorganization of the actin cytoskeleton, formation of cell projections, such as neurites, in neuron morphogenesis and synapse formation via its interaction with WASL and COBL. Does not bind G-actin and promote actin polymerization by itself. Required for the formation of organized podosome rosettes(By similarity). May act as a common effector of antigen receptor-signaling pathways in leukocytes. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes.

IMMUNOGEN INFORMATION

Immunogen

drebrin-like

Synonyms

CMAP, SH3P7

Observed MW

55 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q9UJU6

IMAGES