anti- DBR1 antibody

Our Anti-DBR1 (RNA Lariat Debranching Enzyme) Antibody, available in a 100µg size, is a crucial tool for researchers studying DBR1, an enzyme involved in RNA splicing and the removal of lariat introns. DBR1 plays a pivotal role in maintaining RNA integrity and preventing the accumulation of aberrant RNA species.

Accurate detection of DBR1 is essential for understanding its functions and its impact on RNA processing pathways and cellular responses. This antibody has undergone rigorous validation for specificity and sensitivity, ensuring reliable results in applications such as RNA immunoprecipitation and immunofluorescence.

With its 100µg size, this antibody provides ample material for multiple experiments, allowing you to explore DBR1 expression and function in different cell types and RNA splicing contexts. Trust in the quality of our Anti-DBR1 Antibody to advance your research and deepen your insights into the intricate mechanisms governing RNA biology and genome stability.

Product Name

DBR1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis.

IMMUNOGEN INFORMATION

Immunogen

debranching enzyme homolog 1

Observed MW

62 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q9UK59

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