anti- DBT antibody

Our Anti-DBT (Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex) Antibody, available in a 100µg size, is an essential tool for researchers investigating the role of DBT in mitochondrial energy metabolism and its implications in metabolic disorders. DBT is a key enzyme involved in the citric acid cycle and plays a pivotal role in energy production.

Accurate detection of DBT is crucial for understanding its functions and its impact on metabolic pathways and disease states. This antibody has undergone rigorous validation for specificity and sensitivity, ensuring reliable results in applications such as immunoprecipitation and immunohistochemistry.

With its 100µg size, this antibody provides ample material for multiple experiments, allowing you to explore DBT expression and function in different tissues and under various metabolic conditions. Trust in the quality of our Anti-DBT Antibody to advance your research and deepen your insights into the complex mechanisms of mitochondrial metabolism and metabolic diseases.

Product Name

DBT antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase(E1), lipoamide acyltransferase(E2) and lipoamide dehydrogenase(E3). Within this complex, the catalytic function of this enzyme is to accept, and to transfer to coenzyme A, acyl groups that are generated by the branched-chain alpha-keto acid decarboxylase component.

IMMUNOGEN INFORMATION

Immunogen

dihydrolipoamide branched chain transacylase E2

Synonyms

BCATE2

Observed MW

53kd

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

P11182

IMAGES