anti- DCK antibody

Our Anti-DCK (Deoxycytidine Kinase) Antibody, available in a 100µg size, is an essential tool for researchers studying DCK, a key enzyme involved in the phosphorylation of deoxycytidine and the activation of nucleoside analog prodrugs used in cancer therapy. DCK plays a pivotal role in the sensitivity of cancer cells to nucleoside analog-based chemotherapy.

Accurate detection of DCK is crucial for understanding its functions and its impact on the efficacy of nucleoside analog treatments in cancer patients. This antibody has undergone rigorous validation for specificity and sensitivity, ensuring reliable results in applications such as Western blotting and immunohistochemistry.

With its 100µg size, this antibody provides ample material for multiple experiments, allowing you to explore DCK expression and function in different cancer types and drug response contexts. Trust in the quality of our Anti-DCK Antibody to advance your research and deepen your insights into the complex mechanisms of nucleoside analog activation and cancer therapy.

Product Name

DCK antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.

IMMUNOGEN INFORMATION

Immunogen

deoxycytidine kinase

Observed MW

30 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P27707

IMAGES