anti- DCTPP1 antibody

Our Anti-DCTPP1 (dCTP Pyrophosphatase 1) Antibody, available in a 100µg size, is a crucial tool for researchers investigating the role of DCTPP1 in nucleotide metabolism and its implications in DNA replication and repair.

Accurate detection of DCTPP1 is essential for understanding its functions and its impact on maintaining genomic stability and cellular responses to DNA damage. This antibody has undergone rigorous validation for specificity and sensitivity, ensuring reliable results in applications such as enzyme assays and immunohistochemistry.

With its 100µg size, this antibody provides ample material for multiple experiments, enabling you to explore DCTPP1 expression and function in different cell types and under various DNA repair conditions. Trust in the quality of our Anti-DCTPP1 Antibody to advance your research and gain insights into the complex mechanisms governing nucleotide metabolism and genome integrity.

Product Name

DCTPP1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Hydrolyzes deoxynucleoside triphosphates(dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for modified dCTP. Activity is highest with 5-iodo-dCTP, followed by 5-bromo-dCTP, unmodified dCTP, 5-methyl-dCTP and 5-chloro-dCTP. Hydrolyzes 2-chloro-dATP and 2-hydroxy-dATP with lower efficiency, and has even lower activity with unmodified dATP, dTTP and dUTP(in vitro). Does not hydrolyze ATP, UTP, ITP, GTP, dADP, dCDP or dGTP. May protect DNA or RNA against the incorporation of non-canonical nucleotide triphosphates. May protect cells against inappropriate methylation of CpG islands by DNA methyltransferases(By similarity).

IMMUNOGEN INFORMATION

Immunogen

dCTP pyrophosphatase 1

Synonyms

XTP3TPA

Observed MW

19 kDa ; 40 kDa ; 80 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

Q9H773

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