anti- DCX antibody

Our Anti-DCX (Doublecortin) Antibody, available in a 100µg size, is a critical tool for researchers investigating the role of DCX in neurogenesis and neuronal migration, with implications in brain development and neurodegenerative disorders. DCX is a microtubule-associated protein expressed in neuronal precursor cells and plays a pivotal role in guiding migrating neurons to their appropriate locations.

Accurate detection of DCX is crucial for understanding its functions and its potential involvement in neuronal development and disorders like epilepsy and lissencephaly. This antibody has undergone rigorous validation for specificity and sensitivity, ensuring reliable results in applications such as immunofluorescence and Western blotting.

With its 100µg size, this antibody provides ample material for multiple experiments, allowing you to explore DCX expression and function in different brain regions and developmental stages. Trust in the quality of our Anti-DCX Antibody to advance your research and deepen your insights into the complex processes of neural development and disease pathogenesis.

Product Name

DCX antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration.

IMMUNOGEN INFORMATION

Immunogen

doublecortin

Synonyms

DBCN, DC, DCX, doublecortin, Doublin, Lis X, Lissencephalin X, LISX, SCLH, XLIS

Observed MW

40 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500-1:2000; IF: 1:20-1:200; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

O43602

IMAGES