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SKU:FNab02317

anti- DDX58 antibody

anti- DDX58 antibody

Regular price $330.00 USD
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Introducing our Anti-DDX58 Antibody x2, a powerful research tool available in a 100µg size. This antibody is designed to detect DDX58, also known as RIG-I (Retinoic Acid-Inducible Gene I), a key player in the innate immune response against viral infections.

With this unique x2 formulation, you get twice the detection power for your experiments. DDX58 is a critical RNA helicase involved in recognizing viral RNA and initiating immune responses. Our antibody has undergone stringent validation to ensure specificity and sensitivity, guaranteeing reliable and reproducible results.

Whether you're investigating antiviral immune pathways, studying the host defense against pathogens, or exploring DDX58's role in various diseases, our Anti-DDX58 Antibody x2 empowers your research. With ample supply, you can conduct extensive experiments, gaining deeper insights into the intricate mechanisms of innate immunity.

Product Name

DDX58 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response.

IMMUNOGEN INFORMATION

Immunogen

DEAD (Asp-Glu-Ala-Asp) box polypeptide 58

Observed MW

109 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:20 - 1:100

UNIPROT INFORMATION

UniProt ID

O95786

IMAGES

 

Immunohistochemistry of paraffin-embedded human prostate using FNab02317(DDX58 antibody) at dilution of 1:100
MCF7 cells were subjected to SDS PAGE followed by western blot with FNab02317(DDX58 antibody) at dilution of 1:1000

 

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