anti- DEAF1 antibody

Explore the intricate world of transcriptional regulation with our Anti-DEAF1 Antibody, offered in a 100µg size to support your research endeavors. DEAF1, or Deformed Epidermal Autoregulatory Factor 1, plays a vital role in gene expression control and immune responses.

Our antibody is rigorously validated to ensure its specificity and sensitivity, providing you with reliable results. Whether you're studying immune system function, gene regulation, or neurological disorders, our Anti-DEAF1 Antibody is your invaluable tool. Illuminate the complex pathways of transcriptional regulation and advance your scientific discoveries with confidence.

Product Name

DEAF1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Transcription factor that binds to sequence with multiple copies of 5'-TTC[CG]G-3' present in its own promoter and that of the HNRPA2B1 gene. Down-regulates transcription of these genes. Binds to the retinoic acid response element(RARE) 5'-AGGGTTCACCGAAAGTTCA-3'. Activates the proenkephalin gene independently of promoter binding, probably through protein-protein interaction. When secreted, behaves as an inhibitor of cell proliferation, by arresting cells in the G0 or G1 phase. Required for neural tube closure and skeletal patterning. Regulates epithelial cell proliferation and side-branching in the mammary gland. Controls the expression of peripheral tissue antigens in pancreatic lymph nodes. Isoform 1 displays greater transcriptional activity than isoform 4. Isoform 4 may inhibit transcriptional activity of isoform 1 by interacting with isoform 1 and retaining it in the cytoplasm. Transcriptional activator of EIF4G3.

IMMUNOGEN INFORMATION

Immunogen

deformed epidermal autoregulatory factor 1(Drosophila)

Synonyms

SPN, ZMYND5

Observed MW

60-63 kDa, 72 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

O75398

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