anti- DENND1A antibody

The anti-DENND1A antibody, available in a 100µg size, is a critical tool for researchers exploring the functions of DENND1A (DENN Domain Containing 1A) protein, which is involved in cellular processes such as vesicular trafficking and autophagy.

This antibody is meticulously designed to specifically target DENND1A with exceptional specificity and sensitivity, making it suitable for applications such as Western blotting, immunoprecipitation, and studies related to intracellular trafficking pathways.

Our anti-DENND1A antibody is sourced from high-quality materials and undergoes rigorous validation to ensure reliable and reproducible results. Researchers investigating vesicular trafficking, autophagy, or the role of DENND1A in disease mechanisms will find this antibody indispensable for their work.

With a 100µg size, this antibody provides ample supply for multiple experiments and is compatible with various sample types, including cell lysates and vesicular fractions. Whether exploring DENND1A's function in intracellular trafficking, autophagy regulation, or its implications in pathological conditions, this antibody is a critical resource for your research.

Product Name

DENND1A antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Guanine nucleotide exchange factor(GEF) regulating clathrin-mediated endocytosis through RAB35 activation. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form. Regulates clathrin-mediated endocytosis of synaptic vesicles and mediates exit from early endosomes(PubMed:20154091, PubMed:20937701). Binds phosphatidylinositol-phosphates(PtdInsPs), with some preference for PtdIns(3)P(By similarity).

IMMUNOGEN INFORMATION

Immunogen

DENN/MADD domain containing 1A

Synonyms

FAM31A, KIAA1608

Observed MW

111 kDa, 64 kDa

APPLICATION

Tested Application

ELISA, WB, IF

Recommended Dilution

WB: 1:500-1:2000; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q8TEH3

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