anti- DENR antibody

The anti-DENR antibody, available in a 100µg size, is an essential tool for researchers exploring the functions of the DENR (Density Regulated Re-initiation and Release Factor) protein in cellular processes. DENR is involved in translational regulation and plays a pivotal role in protein synthesis.

This antibody is meticulously designed to specifically target DENR with exceptional specificity and sensitivity, making it ideal for applications such as Western blotting, immunoprecipitation, and studies related to translational control.

Our anti-DENR antibody is sourced from high-quality materials and undergoes rigorous validation to ensure reliable and reproducible results. Researchers investigating protein synthesis, translational regulation, or the role of DENR in disease mechanisms will find this antibody indispensable for their work.

With a 100µg size, this antibody provides ample supply for multiple experiments and is compatible with various sample types, including cell lysates and translational complexes. Whether exploring translational initiation, DENR's role in protein synthesis, or its implications in pathological conditions, this antibody is a critical resource for your research.

Product Name

DENR antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation; promotes recruitmnet of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits. Plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1.

IMMUNOGEN INFORMATION

Immunogen

density-regulated protein

Synonyms

DRP1

Observed MW

27-30kd

APPLICATION

Tested Application

ELISA, WB, IF

Recommended Dilution

WB: 1:500-1:2000; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

O43583

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