anti- DHX36 antibody

The anti-DHX36 antibody, available in a 100µg size, is an indispensable tool for researchers studying DHX36 (DEAH-Box Helicase 36), an RNA helicase involved in RNA metabolism and RNA modification processes.

This antibody is meticulously designed to specifically target DHX36 with exceptional specificity and sensitivity, making it ideal for applications such as Western blotting, immunoprecipitation, and studies related to RNA helicases, small nucleolar RNAs (snoRNAs), and gene expression control.

Our anti-DHX36 antibody is sourced from high-quality materials and undergoes rigorous validation to ensure reliable and reproducible results. Researchers investigating the roles of DHX36 in RNA unwinding, snoRNA binding, or its implications in diseases like cancer will find this antibody indispensable for their work.

With a 100µg size, each vial provides ample supply for multiple experiments, allowing for flexibility in experimental design. Whether deciphering DHX36's function in ribosome biogenesis, RNA modification, or its involvement in diseases like leukemia, this antibody is an essential resource for your research.

Product Name

DHX36 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Proposed to have a global role in regulating mRNA expression including transcriptional regulation and mRNA stability. Binds with high affinity to and resolves tetramolecular RNA and DNA quadruplex structures. Unwinds intramolecular quadruplexes derived from the ZIC1 and the MYC promoters. Binds to quadruplex structures in the promoters of YY1 and ALPL genes and regulates their expression. Binds to telomerase RNA template component(TERC) 5'-end(nucleotides 1-43) and unwinds an internal quadruplex formation in TERC 5'-end to promote P1 helix formation; the P1 helix acts as a template boundary ensuring accurate reverse transcription and is disrupted by quadruplex formation. May be involved in regulation of telomere length. Plays a role in degradation and deadenylation of mRNAs containing in their 3'-UTR the consensus ARE sequence element. May function in sex development and spermatogenesis. May play a role in ossification.

IMMUNOGEN INFORMATION

Immunogen

DEAH(Asp-Glu-Ala-His) box polypeptide 36

Synonyms

DDX36, KIAA1488, MLEL1, RHAU

Observed MW

120 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q9H2U1

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