anti- DIAPH3 antibody

The anti-DIAPH3 antibody, available in a 100µg size, is a valuable tool for researchers studying DIAPH3 (Diaphanous Homolog 3), an essential member of the formin family of proteins involved in actin cytoskeleton dynamics and cellular processes.

This antibody is meticulously designed to specifically target DIAPH3 with exceptional specificity and sensitivity, making it ideal for applications such as Western blotting, immunohistochemistry, and studies related to cell migration, cell division, and cytoskeletal organization.

Our anti-DIAPH3 antibody is sourced from high-quality materials and undergoes rigorous validation to ensure reliable and reproducible results. Researchers investigating the roles of DIAPH3 in cell motility, cancer metastasis, or its implications in neurological disorders will find this antibody indispensable for their work.

With a 100µg size, each vial provides ample supply for multiple experiments, allowing for flexibility in experimental design. Whether exploring DIAPH3's function in neuronal development, cell polarization, or its involvement in diseases like autism spectrum disorders, this antibody is an essential resource for your research.

Product Name

DIAPH3 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Binds to GTP-bound form of Rho and to profilin. Acts in a Rho-dependent manner to recruit profilin to the membrane, where it promotes actin polymerization. It is required for cytokinesis, stress fiber formation, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics(By similarity).

IMMUNOGEN INFORMATION

Immunogen

diaphanous homolog 3(Drosophila)

Synonyms

DIAP3

Observed MW

125-137kd

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q9NSV4

IMAGES