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SKU:FNab02387

anti- DICER1 antibody

anti- DICER1 antibody

Regular price $290.00 USD
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The anti-DICER1 antibody, available in a 100µg size and in the form of a polyclonal antibody, is an indispensable tool for researchers delving into the functions of DICER1, a key enzyme in the biogenesis of microRNAs (miRNAs) and small interfering RNAs (siRNAs).

DICER1 is a critical player in post-transcriptional gene regulation, making this polyclonal antibody a valuable asset for studies related to gene expression control, RNA interference, and miRNA-mediated processes. With exceptional specificity and sensitivity, this antibody is suitable for various applications, including Western blotting, immunoprecipitation, and immunofluorescence.

Our anti-DICER1 polyclonal antibody is sourced from high-quality materials and subjected to rigorous validation to ensure accurate and reproducible results. Researchers investigating the roles of DICER1 in cellular differentiation, cancer biology, or its implications in developmental disorders will find this antibody indispensable for their work.

The 100µg size provides an ample supply for multiple experiments, offering flexibility in experimental design. Whether unraveling DICER1's role in post-transcriptional silencing, epigenetic regulation, or its involvement in diseases like DICER1 syndrome, this polyclonal antibody is a critical resource for your research.

Product Name

DICER1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants.

IMMUNOGEN INFORMATION

Immunogen

dicer 1, ribonuclease type III

Synonyms

DICER, HERNA, KIAA0928

Observed MW

220-250 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500 - 1:1000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

Q9UPY3

IMAGES

 

Immunohistochemistry of paraffin-embedded human lung cancer using FNab02387( DICER1 Antibody) at dilution of 1:200
Immunofluorescent analysis of HepG2 cells, using DICER1 antibody FNab02387 at 1:100 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
K-562 cells were subjected to SDS PAGE followed by western blot with FNab02387(DICER1 antibody) at dilution of 1:1000

 

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