anti- DKK2 antibody

The anti-DKK2 antibody, available in a 100µg size, is a crucial resource for researchers exploring the roles of DKK2 (Dickkopf-Related Protein 2) in developmental biology, tissue regeneration, and its potential implications in disease.

This antibody is expertly designed for high specificity and sensitivity, making it suitable for applications such as Western blotting, immunohistochemistry, and studies investigating DKK2's involvement in tissue homeostasis and signaling pathways.

Our anti-DKK2 antibody is sourced from top-quality materials and undergoes stringent quality control measures to deliver consistent and reliable results. Researchers studying DKK2's functions in Wnt signaling, stem cell biology, or its relevance to disease mechanisms will find this antibody to be an invaluable asset in their research.

With 100µg of product, each vial offers a substantial supply for multiple experiments, providing flexibility and cost-efficiency in your research.

Product Name

DKK2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease(By similarity).

IMMUNOGEN INFORMATION

Immunogen

dickkopf homolog 2

Synonyms

Dickkopf 2, Dickkopf related protein 2, DKK 2, DKK2, hDkk 2

Observed MW

32 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:1000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q9UBU2

IMAGES