anti- DLL4 antibody

The anti-DLL4 antibody, available in a 100µg size, is a crucial tool for researchers investigating DLL4 (Delta-Like Ligand 4), a transmembrane protein involved in various cellular processes, including Notch signaling. This antibody offers high specificity and sensitivity, making it suitable for multiple applications, including immunohistochemistry and flow cytometry.

DLL4 plays pivotal roles in embryonic development, angiogenesis, and tissue regeneration. Researchers can utilize this antibody to explore the expression patterns and functions of DLL4 in various tissues and disease contexts. Understanding DLL4's role in Notch signaling is essential for unraveling its potential implications in cancer, vascular disorders, and regenerative medicine.

Rigorous quality control ensures the reliability and consistency of results, providing researchers with the confidence to advance their scientific investigations. With 100µg of product per vial, it offers an ample supply for multiple experiments, ensuring cost-effectiveness and experimental flexibility.

In summary, the anti-DLL4 antibody is a high-quality reagent that empowers researchers to investigate the roles of DLL4 in development, angiogenesis, and disease. By studying DLL4, researchers can contribute to our understanding of critical cellular pathways and their therapeutic applications.

Product Name

DLL4 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Involved in the Notch signaling pathway as Notch ligand(PubMed:11134954). Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting(PubMed:20616313). Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types(By similarity). During spinal cord neurogenesis, inhibits V2a interneuron fate(PubMed:17728344).

IMMUNOGEN INFORMATION

Immunogen

delta-like 4(Drosophila)

Observed MW

75-80 kDa

APPLICATION

Tested Application

ELISA, WB, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:2000

UNIPROT INFORMATION

UniProt ID

Q9NR61

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