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SKU:FNab02423

anti- DMD antibody

anti- DMD antibody

Regular price $290.00 USD
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The anti-DMD antibody, available in a 100µg size, is a valuable tool for researchers studying DMD (Dystrophin), a critical protein in muscle tissue. This antibody offers high specificity and sensitivity, making it suitable for various applications, including Western blotting and immunohistochemistry.

DMD is essential for maintaining the structural integrity of muscle fibers, and mutations in the DMD gene can lead to muscular dystrophy, a group of debilitating muscle disorders. Researchers can use this antibody to investigate the expression and localization of DMD in healthy and diseased muscle tissues.

Rigorous quality control ensures the reliability and consistency of results, providing researchers with the confidence to pursue their scientific inquiries effectively. With 100µg of product per vial, it offers a sufficient quantity for multiple experiments, ensuring cost-effectiveness and experimental flexibility.

In summary, the anti-DMD antibody is a high-quality reagent that empowers researchers to explore the roles of DMD in muscle biology and its involvement in muscular dystrophy. By studying DMD, researchers can contribute to our understanding of muscle function and the development of therapeutic strategies for muscle-related diseases.

Product Name

DMD antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Anchors the extracellular matrix to the cytoskeleton via F-actin. Ligand for dystroglycan. Component of the dystrophin-associated glycoprotein complex which accumulates at the neuromuscular junction(NMJ) and at a variety of synapses in the peripheral and central nervous systems and has a structural function in stabilizing the sarcolemma. Also implicated in signaling events and synaptic transmission.

IMMUNOGEN INFORMATION

Immunogen

dystrophin

Synonyms

BMD, CMD3B, DMD, DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272, dystrophin

Observed MW

72 kDa

APPLICATION

Tested Application

ELISA, WB, IF,IHC

Recommended Dilution

WB: 1:500-1:5000; IP: 1:500-1:5000; IHC: 1:50-1:500; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P11532

IMAGES

 

Immunohistochemistry of paraffin-embedded human heart tissue slide using FNab02423(DMD Antibody) at dilution of 1:200
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab02423(DMD antibody) at dilution of 1:1000

 

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