anti- DNAJC10 antibody

Explore the intricacies of protein folding and chaperone-assisted processes with our Anti-DNAJC10 Antibody, available in a 100µg size. DNAJC10 (DnaJ Heat Shock Protein Family Member C10) is an essential co-chaperone involved in the maturation of mitochondrial proteins.

This meticulously designed antibody offers exceptional specificity and sensitivity, ensuring accurate detection of DNAJC10 protein in your experiments. Researchers studying mitochondrial protein import, chaperone function, or related areas will appreciate the precision and reliability of this antibody.

Our high-quality Anti-DNAJC10 Antibody undergoes stringent quality control, guaranteeing consistent and reproducible results. Delve into the forefront of protein folding research and gain valuable insights into the role of DNAJC10 in orchestrating the correct folding of mitochondrial proteins.

Product Name

DNAJC10 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. Required for efficient folding of proteins in the endoplasmic reticulum by catalyzing the removal of non-native disulfide bonds formed during the folding of proteins, such as LDLR. Also involved in endoplasmic reticulum-associated degradation(ERAD) by reducing incorrect disulfide bonds in misfolded glycoproteins recognized by EDEM1. Interaction with HSPA5 is required its activity, not for the disulfide reductase activity, but to facilitate the release of DNAJC10 from its substrate. Promotes apoptotic signaling pathway in response to endoplasmic reticulum stress.

IMMUNOGEN INFORMATION

Immunogen

DnaJ(Hsp40) homolog, subfamily C, member 10

Synonyms

ERDJ5

Observed MW

75-80 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q8IXB1

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