anti- DNMT3L antibody

Journey into the epigenetic world of DNA methylation and gene regulation with our meticulously crafted Anti-DNMT3L Antibody, now available in a 100µg size. DNA (cytosine-5-)-methyltransferase 3-like (DNMT3L) is a critical factor that influences DNA methylation patterns and contributes to the establishment of epigenetic marks during development.

This antibody offers exceptional specificity and sensitivity, ensuring precise detection of DNMT3L in your experiments. Whether you're investigating epigenetic regulation, germ cell development, or gene imprinting, this antibody is your key to unraveling the mysteries of these essential biological processes.

Our high-quality Anti-DNMT3L Antibody undergoes stringent quality control to guarantee consistent and reproducible results, enabling you to advance your research with confidence. Delve into the dynamic world of DNA methylation and the central role DNMT3L plays in shaping the epigenome. Whether you're studying embryogenesis, transgenerational epigenetics, or cancer epigenomics, this antibody is an indispensable tool for your research.

Product Name

DNMT3L antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Catalytically inactive regulatory factor of DNA methyltransferases. It is essential for the function of DNMT3A and DNMT3B. Activates DNMT3A and DNMT3B by binding to their catalytic domain. Accelerates the binding of DNA and AdoMet to the methyltransferases and dissociates from the complex after DNA binding to the methyltransferases. Recognizes unmethylated histone H3 lysine 4(H3K4) and induces de novo DNA methylation by recruitment or activation of DNMT3.

IMMUNOGEN INFORMATION

Immunogen

DNA(cytosine-5-)-methyltransferase 3-like

Observed MW

44kd and 70kd

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

Q9UJW3

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