anti- DOC2B antibody

Unlock the secrets of synaptic transmission and neuronal signaling with our meticulously crafted Anti-DOC2B Antibody, now available in a 100µg size. Double C2 domain protein B (DOC2B) plays a pivotal role in calcium-dependent exocytosis, making it a key player in neurotransmitter release and synaptic function.

This antibody offers exceptional specificity and sensitivity, ensuring precise detection of DOC2B in your experiments. Whether you're investigating synaptic plasticity, neuronal communication, or secretory mechanisms, this antibody is your key to uncovering the mysteries of these essential neuronal processes.

Our high-quality Anti-DOC2B Antibody undergoes stringent quality control to guarantee consistent and reproducible results, enabling you to advance your research with confidence. Dive into the dynamic world of neuronal signaling and the central role DOC2B plays in ensuring proper neurotransmission. Whether you're studying neurodegenerative diseases, synaptic disorders, or neurotransmitter regulation, this antibody is an indispensable tool for your research.

Product Name

DOC2B antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Calcium sensor which positively regulates SNARE-dependent fusion of vesicles with membranes. Binds phospholipids in a calcium-dependent manner and may act at the priming stage of fusion by modifying membrane curvature to stimulate fusion. Involved in calcium-triggered exocytosis in chromaffin cells and calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Involved both in glucose-stimulated insulin secretion in pancreatic cells and insulin-dependent GLUT4 transport to the plasma membrane in adipocytes(By similarity).

IMMUNOGEN INFORMATION

Immunogen

double C2-like domains, beta

Synonyms

DOC2BL

Observed MW

46kd

APPLICATION

Tested Application

ELISA, WB, IF

Recommended Dilution

WB: 1:500-1:2000; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q14184

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