anti- DOK7 antibody

Embark on a journey into the intricate world of neuromuscular synapses and the essential role of Downstream of Kinase 7 (DOK7) with our meticulously crafted Anti-DOK7 Antibody, now available in a 100µg size. DOK7 is a critical mediator of the agrin-LRP4-MuSK signaling pathway that regulates the formation and maintenance of neuromuscular junctions.

This antibody offers exceptional specificity and sensitivity, ensuring precise detection of DOK7 in your experiments. Whether you're investigating neuromuscular disorders, synaptic transmission, or muscle development, this antibody is your key to understanding the role of DOK7 in these fundamental biological processes.

Our high-quality Anti-DOK7 Antibody undergoes stringent quality control to guarantee consistent and reproducible results, enabling you to advance your research with confidence. Delve into the dynamic world of neuromuscular synapses and the pivotal role DOK7 plays in shaping these critical cellular connections. Whether you're studying myasthenia gravis, muscular dystrophy, or synaptic plasticity, this antibody is an indispensable tool for your research.

Product Name

DOK7 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor(AchR) clustering in myotubes. Induces autophosphorylation of MUSK.

IMMUNOGEN INFORMATION

Immunogen

docking protein 7

Synonyms

C4orf25

Observed MW

64 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q18PE1

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