anti- DPP4 antibody

Delve into the realm of enzyme research and its implications for metabolic processes with our meticulously designed Anti-DPP4 Antibody, now available in a 100µg size. Dipeptidyl peptidase 4 (DPP4) is a critical enzyme associated with peptide metabolism and is of great interest to researchers studying metabolic disorders and therapeutic strategies.

This highly specific antibody empowers you to explore the complexities of metabolic pathways with precision and confidence. It has undergone rigorous quality control to ensure accuracy and reproducibility in your experiments, making it the ideal choice for researchers investigating metabolic diseases, cancer biology, and peptide metabolism.

DPP4 plays a central role in peptide cleavage and is associated with inflammatory responses and metabolic disorders. Whether you're researching metabolic diseases, cancer therapy, or the mechanisms of peptide metabolism, this antibody will be your trusted companion.

Product Name

DPP4 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor(TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix(ECM), the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, enhanced cell proliferation, a process inhibited by GPC3. Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation, including many chemokines, mitogenic growth factors, neuropeptides and peptide hormones. Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.

IMMUNOGEN INFORMATION

Immunogen

dipeptidyl-peptidase 4

Synonyms

ADABP, ADCP 2, ADCP2, CD26, dipeptidyl peptidase 4, Dipeptidyl peptidase IV, DPP IV, DPP4, DPPIV, T cell activation antigen CD26, TP103

Observed MW

110 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100

UNIPROT INFORMATION

UniProt ID

P27487

IMAGES