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SKU:FNab02573

anti- DVL2 antibody

anti- DVL2 antibody

Regular price $290.00 USD
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Dive into the intricacies of cellular signaling and the Wnt pathway with our meticulously crafted Anti-DVL2 Antibody, now available in a 100µg size. Disheveled 2 (DVL2) is a crucial player in mediating Wnt signaling cascades and is an essential tool for researchers studying developmental biology, tissue regeneration, and cancer biology.

This highly specific antibody empowers you to explore the complexities of DVL2 and its functions with precision and confidence. It has undergone rigorous quality control to ensure accuracy and reproducibility in your experiments, making it an ideal choice for researchers investigating Wnt signaling pathways, tissue homeostasis, and their implications in disease.

DVL2 plays a pivotal role in tissue development and cancer progression, and its dysfunction is often associated with disease conditions. Whether your research focuses on developmental biology, cancer biology, or disease mechanisms, this antibody will be your invaluable research companion.

Product Name

DVL2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes(By similarity).

IMMUNOGEN INFORMATION

Immunogen

dishevelled, dsh homolog 2

Synonyms

Dishevelled 2, DSH homolog 2, DVL2

Observed MW

90 kDa

APPLICATION

Tested Application

ELISA, WB, IF, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:500-1:2000; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

O14641

IMAGES

 

Immunofluorescent analysis of HepG2 cells using FNab02573 (DVL2 antibody) at dilution of 1:50 and Rhodamine-Goat anti-Rabbit IgG
IP Result of anti-DVL2 (IP: FNab02573, 4ug; Detection: FNab02573 1:1000) with MCF-7 cells lysate 3200ug.
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab02573( DVL2 Antibody) at dilution of 1:1000

 

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