anti- E2F3 antibody

Propel your research in cell cycle regulation and transcriptional control with our meticulously crafted Anti-E2F3 Antibody, now available in a 100µg size. E2F3, a member of the E2F transcription factor family, is a key player in cell cycle progression, DNA replication, and gene expression.

This antibody is rigorously tested for specificity, making it an invaluable tool for researchers delving into the intricacies of transcriptional regulation, cell cycle dynamics, and their roles in health and disease.

E2F3's role in cell cycle control and its implications in cancer development have made it a subject of significant research interest. Whether your work is centered on cancer biology, gene regulation, or cell cycle dynamics, this antibody is your trusted companion.

Product Name

E2F3 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F3 binds specifically to RB1 in a cell-cycle dependent manner. Inhibits adipogenesis, probably through the repression of CEBPA binding to its target gene promoters(By similarity).

IMMUNOGEN INFORMATION

Immunogen

E2F transcription factor 3

Synonyms

KIAA0075

Observed MW

52 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

O00716

IMAGES