anti- EAAT2 antibody

Embark on a journey to unravel the mysteries of glutamate transport with our meticulously crafted Anti-EAAT2 Antibody, now available in a 100µg size. EAAT2, also known as Excitatory Amino Acid Transporter 2, is a pivotal protein responsible for regulating glutamate levels in the brain, making it essential for neuronal health and synaptic function.

This antibody is rigorously tested for specificity, ensuring that your research on neurobiology, excitatory neurotransmission, and neurological disorders is supported by a reliable tool.

EAAT2's role in glutamate homeostasis and its implications in conditions like epilepsy and neurodegenerative diseases have made it a subject of significant interest in the field. Whether your research is centered on neuroscience, drug development, or neuroprotection, this antibody is an invaluable addition to your toolkit.

Product Name

EAAT2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

EAAT2 (also known as GLT-1), is encoded by SLC1A2 and is a glutamate transporter which can clear the majority of extracellular glutamate in brain and prevent brain seizures.Three isoforms of EAAT2 exist due to the alternative splicing. In addition to the 65-70 kDa monomer form, 120-140 kDa dimer of EAAT2 can also be observed on SDS-PAGE. (PMID: 22114258)

IMMUNOGEN INFORMATION

Immunogen

solute carrier family 1(glial high affinity glutamate transporter), member 2

Synonyms

EAAT2, EIEE41, GLT-1, HBGT

Observed MW

60-70 kDa, 120 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P43004

IMAGES