anti- EHD3 antibody

Investigate the intricate functions of EHD3 (Eps15 homology domain-containing protein 3) with our Anti-EHD3 Antibody, now available in a 100µg size. EHD3 plays a pivotal role in regulating membrane trafficking, vesicle dynamics, and endocytic processes.

This antibody is meticulously validated for specificity, ensuring that your research on EHD3's roles in endocytosis regulation, its interactions with other vesicle-associated proteins, and its implications in cellular events is backed by a reliable tool.

EHD3's significance in orchestrating vesicle transport and its potential relevance in cellular dynamics have made it a subject of significant research interest. Whether your research focuses on endocytic pathways, vesicle-mediated events, or membrane remodeling mechanisms, this antibody is an indispensable addition to your toolkit.

Order your 100µg vial today and delve into the world of EHD3 to advance your understanding of its functions in cellular processes.

Product Name

EHD3 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

ATP-and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis(PubMed:25686250). In vitro causes tubulation of endocytic membranes(PubMed:24019528). Binding to phosphatidic acid induces its membrane tubulation activity(By similarity). Plays a role in endocytic transport. Involved in early endosome to recycling endosome compartment(ERC), retrograde early endosome to Golgi, and endosome to plasma membrane(rapid recycling) protein transport. Involved in the regulation of Golgi maintenance and morphology(PubMed:16251358, PubMed:17233914, PubMed:19139087, PubMed:23781025). Involved in the recycling of internalized D1 dopamine receptor(PubMed:21791287). Plays a role in cardiac protein trafficking probably implicating ANK2(PubMed:20489164). Involved in the ventricular membrane targeting of SLC8A1 and CACNA1C and probably the atrial membrane localization of CACNA1GG and CACNA1H implicated in the regulation of atrial myocyte excitability and cardiac conduction(By similarity). In conjunction with EHD4 may be involved in endocytic trafficking of KDR/VEGFR2 implicated in control of glomerular function(By similarity). Involved in the rapid recycling of integrin beta-3 implicated in cell adhesion maintenance(PubMed:23781025). Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating a function in neuronal APP processing(By similarity). Plays a role in the formation of the ciliary vesicle, an early step in cilium biogenesis; possibly sharing redundant functions with EHD1(PubMed:25686250).

IMMUNOGEN INFORMATION

Immunogen

EH-domain containing 3

Synonyms

EHD2,

Observed MW

61 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

Q9NZN3

IMAGES