anti- EIF3D antibody

Delve into the fascinating world of gene translation with our Anti-EIF3D Antibody, now available in a 100µg size. EIF3D (Eukaryotic Translation Initiation Factor 3 Subunit D) is an essential component of the eukaryotic translation initiation complex.

This antibody is meticulously validated for specificity, ensuring that your research on EIF3D's role in translation initiation, its interactions with other translation factors, and its implications in various cellular processes is fortified by a reliable tool.

EIF3D's significance in controlling gene expression and orchestrating protein synthesis has made it a subject of substantial research interest. Whether your research focuses on translation initiation, ribosome assembly, or gene regulation, this antibody is an indispensable addition to your toolkit.

Order your 100µg vial today and unravel the mechanisms of EIF3D in cellular processes.

Product Name

EIF3D antibody

Size

100µg

Form

liquid

Purification

Protein A+G purification

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG1

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Component of the eukaryotic translation initiation factor 3(eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex(43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. In case of FCV infection, plays a role in the ribosomal termination-reinitiation event leading to the translation of VP2(PubMed:18056426).

IMMUNOGEN INFORMATION

Immunogen

eukaryotic translation initiation factor 3, subunit D

Synonyms

EIF3S7

Observed MW

66 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

O15371

IMAGES