anti- EIF3E antibody

Decipher the intricate language of genes with our Anti-EIF3E Antibody, now available in a 100µg size. EIF3E (Eukaryotic Translation Initiation Factor 3 Subunit E) is a crucial component of the eukaryotic translation initiation complex.

This antibody is rigorously validated for specificity, ensuring that your research on EIF3E's role in translation initiation, its interactions with other translation factors, and its implications in various cellular processes is supported by a reliable tool.

EIF3E's significance in controlling gene expression and protein synthesis has made it a subject of substantial research interest. Whether your research delves into translation initiation, ribosome assembly, or gene regulation, this antibody is an essential addition to your toolkit.

Order your 100µg vial today and delve into the language of genes to advance your understanding of cellular processes.

Product Name

EIF3E antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Component of the eukaryotic translation initiation factor 3(eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex(43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. Required for nonsense-mediated mRNA decay(NMD); may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. May interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins.

IMMUNOGEN INFORMATION

Immunogen

eukaryotic translation initiation factor 3, subunit E

Synonyms

EIF3S6,

Observed MW

48-52kd

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P60228

IMAGES