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SKU:FNab02710

anti- EIF3I antibody

anti- EIF3I antibody

Regular price $290.00 USD
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Explore EIF3I (Eukaryotic Translation Initiation Factor 3 Subunit I) with our Anti-EIF3I Antibody, now available in a 100µg size. EIF3I is a critical subunit of the eukaryotic translation initiation factor 3 complex, essential for the initiation of protein synthesis and the regulation of gene expression.

This antibody is meticulously validated for specificity, ensuring that your research on EIF3I's role in translation initiation, its interactions with other translation factors, and its implications in various cellular processes is strengthened by a reliable tool.

EIF3I's significance in orchestrating gene expression and controlling protein synthesis has made it a subject of substantial research interest. Whether your studies delve into translation initiation, ribosome assembly, or gene regulation, this antibody is an indispensable addition to your scientific toolkit.

Order your 100µg vial today and delve into the exploration of EIF3I's multifaceted functions in gene regulation and protein synthesis.

Product Name

EIF3I antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Component of the eukaryotic translation initiation factor 3(eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex(43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

IMMUNOGEN INFORMATION

Immunogen

eukaryotic translation initiation factor 3, subunit I

Synonyms

EIF3S2, TRIP1

Observed MW

36kd

APPLICATION

Tested Application

ELISA, IHC, IF, IP, WB, FC

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q13347

IMAGES

 

Immunohistochemistry of paraffin-embedded human breast cancer using FNab02710(EIF3I antibody) at dilution of 1:100
IP Result of anti-EIF3I (IP:FNab02710, 3ug; Detection:FNab02710 1:1000) with HEK-293 cells lysate 1500ug.
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab02710(EIF3I antibody) at dilution of 1:1000

 

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