anti- EIF3J antibody

Unveil the functional significance of EIF3J (Eukaryotic Translation Initiation Factor 3 Subunit J) with our Anti-EIF3J Antibody, now available in a 100µg size. EIF3J is a vital component of the eukaryotic translation initiation factor 3 complex, crucial for the initiation of protein synthesis and the regulation of gene expression.

This antibody is rigorously validated for specificity, ensuring that your research on EIF3J's involvement in translation initiation, its interactions with other translation factors, and its implications in various cellular processes is fortified by a reliable tool.

EIF3J's significance in orchestrating gene expression and controlling protein synthesis has made it a subject of substantial research interest. Whether your studies delve into translation initiation, ribosome assembly, or gene regulation, this antibody is an indispensable addition to your scientific toolkit.

Order your 100µg vial today and advance your research into EIF3J's multifaceted functions in gene regulation and protein synthesis.

Product Name

EIF3J antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Component of the eukaryotic translation initiation factor 3(eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex(43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. This subunit binds directly within the mRNA entry channel of the 40S ribosome to the aminoacyl(A) site. It may regulate the interaction between the 43S PIC and mRNA.

IMMUNOGEN INFORMATION

Immunogen

eukaryotic translation initiation factor 3, subunit J

Synonyms

EIF3S1

Observed MW

35 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

O75822

IMAGES