anti- EIF3M antibody

Uncover the functional significance of EIF3M (Eukaryotic Translation Initiation Factor 3 Subunit M) with our Anti-EIF3M Antibody, now available in a 100µg size. EIF3M is a subunit of the eukaryotic translation initiation factor 3 complex, essential for the initiation of protein synthesis and the regulation of gene expression.

This antibody is meticulously validated for specificity, ensuring that your research on EIF3M's involvement in translation initiation, its interactions with other translation factors, and its implications in various cellular processes is fortified by a reliable tool.

EIF3M's significance in orchestrating gene expression and controlling protein synthesis has made it a subject of substantial research interest. Whether your studies focus on translation initiation, ribosome assembly, or gene regulation, this antibody is an indispensable addition to your scientific toolkit.

Order your 100µg vial today and advance your research into EIF3M's multifaceted functions in gene regulation and protein synthesis.

Product Name

EIF3M antibody

Size

100µg

Form

liquid

Purification

Protein A+G purification

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG1

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Component of the eukaryotic translation initiation factor 3(eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex(43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. May favor virus entry in case of infection with herpes simplex virus 1(HSV1) or herpes simplex virus 2(HSV2).

IMMUNOGEN INFORMATION

Immunogen

eukaryotic translation initiation factor 3, subunit M

Synonyms

HFLB5, PCID1

Observed MW

43 kDa

APPLICATION

Tested Application

ELISA, WB, IF

Recommended Dilution

WB: 1:500-1:2000; IF: 1:10-1:100

UNIPROT INFORMATION

UniProt ID

Q7L2H7

IMAGES