anti- EIF4G1 antibody

Unlock the secrets of translation with our anti-EIF4G1 antibody. This crucial protein plays a central role in the initiation of protein synthesis, making it indispensable for cellular processes. Our antibody, available in a 100µg size, is your key to studying EIF4G1 effectively.

EIF4G1, also known as eukaryotic translation initiation factor 4 gamma 1, is pivotal in assembling the translation initiation complex. By using this antibody, you can delve into its interactions, functions, and significance within the realm of molecular biology.

Whether you're conducting research, diagnostics, or drug development, our anti-EIF4G1 antibody empowers you with precise and reliable results. It's designed for flexibility, suitable for various applications.

Product Name

EIF4G1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage.

IMMUNOGEN INFORMATION

Immunogen

eukaryotic translation initiation factor 4 gamma, 1

Synonyms

EIF4F, EIF4G, EIF4GI

Observed MW

230 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

Q04637

IMAGES