anti- ELK4 antibody

Unlock the complexities of transcriptional regulation with our anti-ELK4 antibody. ELK4, or ETS Like-1 protein, is a transcription factor that plays a crucial role in gene expression. This 100µg antibody is your indispensable tool for investigating the functions and interactions of ELK4.

Investigate how ELK4 binds to DNA and regulates the expression of target genes, influencing processes such as cell proliferation, differentiation, and development. Our meticulously designed antibody ensures precise and reliable results across a range of applications, from chromatin immunoprecipitation to immunofluorescence.

Explore the significance of ELK4 in cancer, immune responses, and neuronal development, and delve into its potential as a therapeutic target. Whether you're involved in basic research or translational studies, this antibody empowers you with the tools to advance your scientific journey.

Product Name

ELK4 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Involved in both transcriptional activation and repression. Interaction with SIRT7 leads to recruitment and stabilization of SIRT7 at promoters, followed by deacetylation of histone H3 at 'Lys-18'(H3K18Ac) and subsequent transcription repression. Forms a ternary complex with the serum response factor(SRF). Requires DNA-bound SRF for ternary complex formation and makes extensive DNA contacts to the 5'side of SRF, but does not bind DNA autonomously.

IMMUNOGEN INFORMATION

Immunogen

ELK4, ETS-domain protein(SRF accessory protein 1)

Synonyms

SAP1

Observed MW

47kd

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

P28324

IMAGES