anti- EME1 antibody

Uncover the secrets of DNA repair and recombination with our anti-EME1 antibody. EME1, or Essential Meiotic Structure-Specific Endonuclease 1, plays a crucial role in maintaining genomic stability and DNA double-strand break repair. This 100µg antibody is your indispensable tool for investigating the functions and interactions of EME1.

Investigate how EME1 participates in DNA repair processes, impacting genomic integrity and cellular responses to DNA damage. Our meticulously designed antibody ensures accurate and reliable results in research applications, from immunofluorescence to chromatin immunoprecipitation.

Explore the significance of EME1 in cancer susceptibility, genetic disorders, and the cellular response to genotoxic stress. Whether you're engaged in basic research or diagnostics, this antibody empowers you to advance your understanding of EME1's role in genome stability.

Product Name

EME1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks.

IMMUNOGEN INFORMATION

Immunogen

essential meiotic endonuclease 1 homolog 1(S. pombe)

Synonyms

MMS4

Observed MW

65 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

Q96AY2

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