anti- EMG1 antibody

Explore the world of ribosome biogenesis with our anti-EMG1 antibody. EMG1, or Essential for Mitotic Growth 1, is a critical player in ribosome assembly, essential for cellular processes. This 100µg antibody is your essential tool for investigating the functions and interactions of EMG1.

Investigate how EMG1 participates in ribosome maturation, influencing processes like protein synthesis and cell growth. Our meticulously designed antibody ensures accurate and reproducible results in various research applications, from immunoprecipitation to western blotting.

Delve into the significance of EMG1 in cell proliferation, nucleolar biology, and its potential associations with diseases such as cancer. Whether you're involved in basic research, diagnostics, or drug development, this antibody equips you with the reliability and reproducibility needed for your scientific inquiries.

Product Name

EMG1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

S-adenosyl-L-methionine-dependent pseudouridine N(1)-methyltransferase that methylates pseudouridine at position 1248(Psi1248) in 18S rRNA. Involved the biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine(m1acp3-Psi) conserved in eukaryotic 18S rRNA. Is not able to methylate uridine at this position(PubMed:20047967). Has also an essential role in 40S ribosomal subunit biogenesis independent on its methyltransferase activity, facilitating the incorporation of ribosomal protein S19 during the formation of pre-ribosomes(By similarity).

IMMUNOGEN INFORMATION

Immunogen

EMG1 nucleolar protein homolog

Synonyms

C2F

Observed MW

27 kDa

APPLICATION

Tested Application

ELISA, WB, IF

Recommended Dilution

WB: 1:500-1:2000; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q92979

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