anti- Endostatin antibody

Uncover the regulatory mysteries of angiogenesis with our anti-Endostatin antibody. Endostatin, an endogenous inhibitor of blood vessel formation, plays a critical role in controlling angiogenesis. With 100µg of this antibody, you have a powerful tool to delve into Endostatin's functions and interactions.

Investigate how Endostatin influences tumor growth, metastasis, and its significance in cancer research. Whether you're involved in basic research, diagnostics, or drug development, our antibody is designed to deliver precise and reliable results across applications.

Trust in our commitment to quality and accuracy as you explore the multifaceted world of Endostatin.

Product Name

Endostatin antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Endostatin is a naturally-occurring 20-kDa C-terminal fragment derived from COL18A1(also named as KNO). It is reported to serve as an anti-angiogenic agent, similar to angiostatin and thrombospondin. It potently inhibits endothelial cell proliferation and inhibits endothelial cell angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling. Endostatin is a broad spectrum angiogenesis inhibitor and may interfere with the pro-angiogenic action of growth factors such as basic fibroblast growth factor(bFGF/FGF-2) and vascular endothelial growth factor(VEGF).

IMMUNOGEN INFORMATION

Immunogen

collagen, type XVIII, alpha 1

Synonyms

Endostatin

Observed MW

19 kDa, 27 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:200-1:1000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P39060

IMAGES