anti- Endothelin 1 antibody

Delve into the fascinating world of vascular regulation with our anti-Endothelin 1 antibody. Endothelin 1, a potent vasoconstrictor and pivotal in cardiovascular physiology, can be explored using this 100µg antibody.

Investigate its functions, interactions, and significance in cardiovascular health and disease. Whether you're engaged in research, diagnostics, or drug development, our antibody is designed to provide accurate and reliable results across applications.

Trust in our commitment to quality as you decipher the roles of Endothelin 1 in vascular biology and its impact on human health.

Product Name

Endothelin 1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.

IMMUNOGEN INFORMATION

Immunogen

endothelin 1

Synonyms

EDN1, endothelin 1, ET 1 Big endothelin 1, ET1, HDLCQ7, PPET1, Preproendothelin 1

Observed MW

24 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

UNIPROT INFORMATION

UniProt ID

P05305

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