anti- ENPP6 antibody

Uncover the complexities of nucleotide metabolism with our Anti-ENPP6 Antibody. This 100µg antibody is your essential tool for investigating ENPP6 (Ectonucleotide Pyrophosphatase/Phosphodiesterase 6), a protein involved in hydrolyzing nucleotide substrates and regulating extracellular nucleotide levels.

ENPP6 plays a crucial role in maintaining nucleotide homeostasis, influencing various physiological processes. Our antibody is rigorously tested for specificity and sensitivity, ensuring accurate results for techniques like immunoblotting, immunoprecipitation, and immunofluorescence.

The Anti-ENPP6 Antibody offers the precision and reliability needed for your research, whether you're focused on fundamental biological studies or exploring therapeutic strategies. This antibody is your key to understanding the functions of ENPP6 and its contribution to nucleotide metabolism.

Product Name

ENPP6 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Choline-specific glycerophosphodiester phosphodiesterase. The preferred substrate may be lysosphingomyelin(By similarity). Hydrolyzes lysophosphatidylcholine(LPC) to form monoacylglycerol and phosphorylcholine but not lysophosphatidic acid, showing it has a lysophospholipase C activity. Has a preference for LPC with short(12:0 and 14:0) or polyunsaturated(18:2 and 20:4) fatty acids. Also hydrolyzes glycerophosphorylcholine and sphingosylphosphorylcholine efficiently. Hydrolyzes the classical substrate for phospholipase C, p-nitrophenyl phosphorylcholine in vitro, while it does not hydrolyze the classical nucleotide phosphodiesterase substrate, p-nitrophenyl thymidine 5'-monophosphate. Does not hydrolyze diacyl phospholipids such as phosphatidylethanolamine, phosphatidylinositol, phosphatidylserine, phosphatidylglycerol and phosphatidic acid.

IMMUNOGEN INFORMATION

Immunogen

ectonucleotide pyrophosphatase/phosphodiesterase 6

Observed MW

50 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

Q6UWR7

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