anti- ENSA antibody

Embark on a journey of cellular regulation with our Anti-ENSA Antibody. This 100µg antibody is your essential tool for investigating ENSA (Endosulfine Alpha), a protein involved in the control of various cellular processes, including cell cycle progression and protein phosphatase activity.

ENSA plays a pivotal role in fine-tuning the balance between kinase and phosphatase activity, influencing cellular signaling and function. Our antibody is meticulously tested for specificity and sensitivity, ensuring accurate results for techniques like immunoblotting, immunoprecipitation, and immunofluorescence.

The Anti-ENSA Antibody offers the precision and reliability needed for your research, whether you're focused on fundamental cellular studies or exploring therapeutic strategies. This antibody is your key to understanding the functions of ENSA and its contribution to cellular regulation.

Product Name

ENSA antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A(PP2A) during mitosis. When phosphorylated at Ser-67 during mitosis, specifically interacts with PPP2R2D(PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase(By similarity). Also acts as a stimulator of insulin secretion by interacting with sulfonylurea receptor(ABCC8), thereby preventing sulfonylurea from binding to its receptor and reducing K(ATP) channel currents.

IMMUNOGEN INFORMATION

Immunogen

endosulfine alpha

Observed MW

19 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

O43768

IMAGES