anti- ER antibody

Unlock the mysteries of estrogen receptor biology and hormone signaling with our Anti-ER Antibody, an essential tool for your research needs. With 100µg of high-quality antibody, you have the precision and reliability required for your experiments.

Estrogen receptors (ERs) are pivotal in regulating hormonal responses, impacting various physiological processes and influencing cancer development. Our antibody is meticulously tested for specificity and sensitivity, making it ideal for techniques such as immunoblotting, immunoprecipitation, and immunofluorescence.

The Anti-ER Antibody is your key to understanding the functions of ERs and their contributions to hormone-related biology and cancer research. Whether you're involved in basic research or hormone therapy development, this antibody is an invaluable asset, providing you with the confidence to advance your scientific inquiries and make significant strides in your work.

Product Name

ER antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.

IMMUNOGEN INFORMATION

Immunogen

estrogen receptor 1

Synonyms

DKFZp686N23123, ER, ER alpha, Era, ESR, ESR1, ESRA, Estradiol receptor, Estrogen receptor, estrogen receptor 1, NR3A1

Observed MW

70 kDa

APPLICATION

Tested Application

ELISA, IHC, WB

Recommended Dilution

WB: 1:1000 - 1:4000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P03372

IMAGES