anti- ERAB antibody

Delve into the world of fatty acid metabolism and cellular energy production with our Anti-ERAB Antibody, a high-quality 100µg monoclonal antibody. ERAB is a key enzyme in the beta-oxidation pathway, playing a critical role in the breakdown of fatty acids to produce energy.

This monoclonal antibody has been rigorously tested for specificity and sensitivity, making it suitable for techniques such as immunoblotting, immunoprecipitation, and immunofluorescence. Whether you're conducting basic research or investigating metabolic diseases, this antibody offers the precision and reliability needed for successful experiments and meaningful discoveries.

The Anti-ERAB Monoclonal Antibody is your key to understanding the functions of ERAB and its contributions to cellular energy production.

Product Name

ERAB antibody

Size

100µg

Form

liquid

Purification

Protein A+G purification

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG1

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/TRMT10C, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. Catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease(AD).

IMMUNOGEN INFORMATION

Immunogen

hydroxysteroid(17-beta) dehydrogenase 10

Synonyms

17 beta HSD 10, 17b HSD10, ABAD, CAMR, DUPXp11.22, ERAB, HADH2, HCD2, HSD17B10, MHBD, MRPP2, MRX17, MRX31, MRXS10, SCHAD, SDR5C1, Type II HADH, XH98G2

Observed MW

27 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:1000-1:4000

UNIPROT INFORMATION

UniProt ID

Q99714

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