anti- ERCC1 antibody

Uncover the mysteries of DNA repair and genomic stability with our Anti-ERCC1 Antibody, an essential tool for studying ERCC1, a crucial component of the DNA repair machinery. With 100µg of high-quality antibody, you have the precision and reliability required for your experiments.

ERCC1 is a key player in repairing DNA damage, preventing mutations, and safeguarding genomic integrity. Our antibody is rigorously tested for specificity and sensitivity, making it ideal for techniques such as immunoblotting, immunoprecipitation, and immunofluorescence.

The Anti-ERCC1 Antibody is your essential tool for exploring ERCC1's functions with precision, contributing to a deeper understanding of DNA repair and genome maintenance. Whether you're engaged in basic research or oncology studies, this antibody is a valuable asset, providing you with the confidence to advance your scientific inquiries and make significant strides in your work.

Product Name

ERCC1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Isoform 1: Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links(ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair(HDR) of DNA double-strand breaks, in conjunction with SLX4.

IMMUNOGEN INFORMATION

Immunogen

excision repair cross-complementing rodent repair deficiency, complementation group 1(includes overlapping antisense sequence)

Observed MW

36-38 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P07992

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